Syllabus | Pharmaceutical Organic Chemistry III – Theory | B. Pharmacy

Course B. Pharmacy 4th semester / 2nd year    
Name of Subject Pharmaceutical Organic Chemistry III – Theory    
Subject Code BP401T BP401T  
Units Topic Domain Hours
1 Stereo isomerism

Optical isomerism – Optical activity, enantiomerism, diastereoisomerism, meso compounds Elements of symmetry, chiral and achiral molecules

 

DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers

Reactions of chiral molecules

 Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute

 

Must Know

 

Desirable

 

Must Know

 

Must Know

Must Know

10
2 Geometrical isomerism

Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)

Methods of determination of configuration of geometrical isomers. Conformational isomerism in Ethane, n-Butane and Cyclohexane.

Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity.

-Stereospecific and stereoselective reactions

 

Must Know

 

Must Know

 

Must know

 

Must Know

10
3 Heterocyclic compounds:

Nomenclature and classification

Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrrole, Furan, and Thiophene – Relative aromaticity, reactivity and Basicity of pyrrole

Must Know Must Know Must Know Must Know Must Know 10
4 Synthesis, reactions and medicinal uses of following compounds/derivatives Pyrazole, Imidazole, Oxazole and Thiazole.

Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives

Must Know

 

 

 

Must Know

8
5 Reactions of synthetic importanc

Metal hydride reduction (NaBH4 and LiAlH4), Clemmensenreduction, Birch reduction, Wolff Kishner reduction.

Oppenauer-oxidation and Dakin reaction.

Beckmanns rearrangement and Schmidt rearrangement. Claisen-Schmidt condensation

Must Know

 

Must Know

7
Admission 2017