Syllabus | Pharmaceutical Organic Chemistry II – Theory | B. Pharmacy

Course

B. Pharmacy  3rd semester / 2nd year

 

Name of Subject

Pharmaceutical Organic Chemistry II – Theory

 

Subject Code

BP301T

 

Units

 

Domain Hours
1 Benzene and its derivatives
Analytical, synthetic and other evidences in the derivation of structure of benzene
Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule
Reactions of benzene – nitration, sulphonation, halogenation-reactivity, Friedel crafts alkylation- reactivity, limitations, Friedelcrafts acylation.Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reactionStructure and uses of DDT, Saccharin, BHC and Chloramine
 

Must Know
Desirable
Must Know
Must Know
Must Know
Must Know

10
2 Phenols – Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses of phenol, cresols, resorcinol, naphthols

Aromatic Amines – Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts

 

Must Know
Must Know
Must

10
3 Fatty acids – reactions.

Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.

Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and principle involved in their determination.

 

Must Know Must Know Must Know Must Know Must Know Must Know

10
4 •      Polynuclear hydrocarbons:

a.     Synthesis, reactions

b.     Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives.

Must Know
Must Know
Must Know
8
5 Cyclo alkanes
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only
 

Must Know Must Know

7