Syllabus | Pharmaceutical Organic Chemistry I – Theory | B. Pharmacy

 

B. Pharmacy Semester2nd  / 1st Year

   
 

Pharmaceutical Organic Chemistry I – Theory

   
 

BP202T

   
Units Topics (Experiments) Domain Hours
1 Classification, nomenclature and isomerism

Classification of Organic Compounds

Common and IUPAC systems of nomenclature of organic compounds  (up to 10 Carbons open chain and carbocyclic compounds)

Structural isomerisms in organic compounds

Must know

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Desirable

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12
2 Alkanes, Alkenes, Conjugated dienes

SP3 hybridization in alkanes,

Halogenation of alkanes,

uses of paraffins.

Stabilities of alkenes,

SP2 hybridization in alkenes

E1 and E2 reactions – kinetics, order of reactivity of alkyl halides, rearrangement of carbocations, Saytzeffs orientation and evidences.

E1 verses E2 reactions, Factors affecting E1 and E2 reactions. Ozonolysis, electrophilic addition reactions of alkenes, Markownikoff’s orientation, free radical addition reactions of alkenes, Anti Markownikoff’s orientation.

Stability of conjugated dienes, Diel-Alder, electrophilic addition, free radical addition reactions of conjugated dienes, allylic rearrangement

 

 

Must know

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Desirable Must know

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16
3 Alkyl halides*

SN1 and SN2 reactions – kinetics, order of reactivity of alkyl halides, stereochemistry and rearrangement of carbocations.

SN1 versus SN2 reactions, Factors affecting SN1 and SN2 reactionsStructure and uses of ethylchloride, Chloroform, trichloroethylene, tetrachloroethylene, dichloromethane, tetrachloromethane and iodoform.

·        Alcohols*- Qualitative tests, Structure and uses of Ethyl alcohol, chlorobutanol, Cetosteryl alcohol, Benzyl alcohol, Glycerol, Propylene glycol

 

 

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12
4 Nucleophilic addition, Electromeric effect, aldol condensation, Crossed Aldol condensation, Cannizzaro reaction, Crossed Cannizzaro reaction, Benzoin condensation, Perkin condensation, qualitative tests,

Structure and uses of Formaldehyde, Paraldehyde, Acetone, Chloral hydrate, Hexamine, Benzaldehyde, Vanilin, Cinnamaldehyde.

Must know

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Desirable

 

12
5 ·        Carboxylic acids*

Acidity of carboxylic acids, effect of substituents on acidity, inductive effect and qualitative tests for carboxylic acids ,amide and ester

Structure and Uses of Acetic acid, Lactic acid, Tartaric acid, Citric acid, Succinic acid. Oxalic acid, Salicylic acid, Benzoic acid, Benzyl benzoate, Dimethyl phthalate, Methyl salicylate and Acetyl salicylic acid

·        Aliphatic amines- Basicity, effect of substituent on Basicity. Qualitative test, Structure and uses of Ethanolamine, Ethylenediamine, Amphetamine

 

 Nice to know

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Admission 2017