Syllabus | Pharmaceutical Engineering ( Theory) | B. Pharmacy

Course : B Pharmacy 3rd semester / 2nd year

Name of Subject: Pharmaceutical Engineering ( Theory)

Subject Code: BP304T

Sr. No.


Domains Time
1. Flow of fluids: Types of manometers, Reynolds number and its significance,  Bernoulli’s  theorem  and  its  applications,  Energy  losses,  Orifice  meter,  Venturimeter, Pitot tube and Rotometer. Must to know 2
2 Size Reduction: Objectives, Mechanisms & Laws governing size reduction, factors affecting size reduction, principles, construction, working, uses, merits and demerits of Hammer mill, ball mill, fluid energy mill, Edge runner mill & end runner mill.   3
3 Size Separation: Objectives, applications & mechanism of size separation, official standards of powders, sieves, size separation Principles, construction, working, uses, merits and demerits of Sieve shaker, cyclone separator, Air separator, Bag filter & elutriation tank. Must to know 2
4 Mixing: Objectives, applications & factors affecting mixing, Difference between solid and liquid mixing, mechanism of solid mixing, liquids mixing and semisolids mixing. Principles, Construction, Working, uses, Merits and Demerits of Double cone blender, twin shell blender, ribbon blender, Sigma blade mixer, planetary mixers, Propellers, Turbines, Paddles & Silverson Emulsifier Must to know 3
5 Crystallization: Objectives, applications, & theory of crystallization. Solubility curves, principles, construction, working, uses, merits and demerits of Agitated batch crystallizer, Swenson Walker Crystallizer, Krystal crystallizer, Vacuum crystallizer. Caking of crystals, factors affecting caking & prevention of caking. Desirable to know 3
6 Heat Transfer: Objectives, applications & Heat transfer mechanisms. Fourier’s law, Heat transfer by conduction, convection & radiation. Heat interchangers & heat exchangers Nice to know 3
7 Evaporation: Objectives, applications and factors influencing evaporation, differences between evaporation and other heat process. principles, construction, working, uses, merits and demerits of Steam jacketed kettle, horizontal tube evaporator, climbing film evaporator, forced circulation evaporator, multiple effect evaporator& Economy of multiple effect evaporator. Must to know 4
8 Drying: Objectives, applications & mechanism of drying process, measurements & applications of Equilibrium Moisture content, rate of drying curve. principles, construction, working, uses, merits and demerits of Tray dryer, drum dryer spray dryer, fluidized bed dryer, vacuum dryer, freeze dryer. Desirable to know 5
9 Distillation: Objectives, applications & types of distillation. principles, construction, working, uses, merits and demerits of (lab scale and industrial scale) Simple distillation, preparation of purified water and water for injection BP by distillation, flash distillation, fractional distillation, distillation under reduced pressure, steam distillation & molecular distillation Must to know 5
10 Filtration: Objectives, applications, Theories & Factors influencing filtration, filter aids, filter medias. Principle, Construction, Working, Uses, Merits and demerits of plate & frame filter, filter leaf, rotary drum filter, Meta filter & Cartridge filter, membrane filters and Seidtz filter.             Must to know 4
11 Centrifugation: Objectives, principle & applications of Centrifugation, principles, construction, working, uses, merits and demerits of Perforated basket centrifuge, Non-perforated basket centrifuge, semi continuous centrifuge & super centrifuge. Nice to know 4
12 Plant location: industrial hazards and plant safety: Plant Layout, utilities and services, Mechanical hazards, Chemical hazards, Fire hazards, explosive hazards and their safety. Nice to know 2
13 Materials of pharmaceutical plant construction: Corrosion and its prevention: Factors affecting during materials selected for Pharmaceutical plant construction, Theories of corrosion, types of corrosion and there prevention. Ferrous and nonferrous metals, inorganic and organic non metals. Nice to know 3
14 Material handling systems: Objectives & applications of Material handling systems, different types of conveyors such as belt, screw and pneumatic conveyors. Desirable to know 2