Syllabus | Pharmaceutical Biotechnology (Theory) | B. Pharmacy

  Course: B Pharmacy 6th Semester /3rd Year,  
  Name of the Subject: Pharmaceutical Biotechnology (Theory)  
  Subject Code: BP605T  
Unit Topic (Contents)             Domain Time (Hrs)
1 Brief introduction to Biotechnology with reference to Pharmaceutical Sciences. Must Know 1
  Enzyme Biotechnology- Methods of enzyme immobilization and applications.            Must Know 2
  Biosensors- Working and applications of biosensors in Pharmaceutical Industries.

 

Must Know 2
  Brief introduction to Protein Engineering. Must Know 1
  Use of microbes in industry. Production of Enzymes- General consideration – Amylase, Catalase, Peroxidase, Lipase, Protease, Penicillinase. Must Know 2
  Basic principles of genetic engineering Must Know 2
2 Study of cloning vectors, restriction endonucleases and DNA ligase. Must Know 2
  Recombinant DNA technology. Application of genetic engineering in medicine. Must Know 2
  Application of r DNA technology and genetic engineering in the products:

Interferon b) Vaccines- hepatitis- B c) Hormones- Insulin

Must Know 2
  Brief introduction to PCR Must Know 2
  Types of immunity-humoral immunity, cellular immunity. Must Know 2
3 Structure of Immunoglobulins,  Structure and Function of MHC Must Know 2
  Hypersensitivity reactions, Immune stimulation and Immune suppressions. Must Know 2
  General method of the preparation of bacterial vaccines, toxoids, viral vaccine, antitoxins, serum-immune blood derivatives and other products relative to immunity. Must Know 2
  Storage conditions and stability of official vaccines Must Know 2
  Hybridoma technology- Production, Purification and Applications Nice to Know 2
4 Immuno blotting techniques- ELISA, Western blotting, Southern blotting. Must Know 2
  Genetic organization of Eukaryotes and Prokaryotes            Must Know 1
  Microbial genetics including transformation, transduction, conjugation, plasmids and transposons. Must Know 2
  Introduction to Microbial biotransformation and applications. F Must Know 2
  Mutation. Must Know 1
5 Types of mutation/mutants Must Know 1
  Fermentation methods and general requirements, study of media, equipments, sterilization methods, aeration process, stirring. Must Know 2
  Large scale production fermenter design and its various controls. Must Know 2
  Study of the production of – penicillins, citric acid, Vitamin B12, Glutamic acid, Griseofulvin, Must Know 2