Course: B. Pharmacy VIth Semester/ 2nd Year 
Name of Subject: Physical PharmaceuticsII (Practical) 
Subject Code: BP 407 P 
Sr. No. 
Contents of the Topics 
Learning objectives  Teaching Guidelines  Methodology  Time (Hrs) 

Determination of particle size by optical method.  At the end of the practical student should be able to demonstrate the experiment on particle size  To find out the particle size of given sample of powder  Hands on practical session  4 

Determination of particle size by sieving method and efficiency of screening operation.  At the end of the practical student should be able to demonstrate the experiment on particle size  To find out the particle size of given sample of powder by different sets of sieves and determine its efficacy.  Hands on practical session  4 

Determination of particle size by sedimentation method using and Andreessen pipette.  At the end of the practical student should be able to demonstrate the experiment on particle size  To find out the particle size of given sample of powder by sedimentation method.  Hands on practical session  4 

Determination of flow properties of powder through the tube as a function of length of tube, diameter of orifice of tube and pressure head.  At the end of the practical student should be able to demonstrate the experiment on flow properties of powders  To find out the flow properties of given sample.  Hands on practical session  4 

To determine the distribution coefficient of benzoic acid between water – benzene system.  At the end of the practical student should be able to demonstrate the experiment on distribution coefficient  Find out the partition coefficient of benzoic acid between water – benzene system.  Hands on practical session  4 

Experiments demonstrating the measurement of angle of repose of powders and the factors affecting.  At the end of the practical student should be able to demonstrate the experiment on flow properties of powders  To find out the flow properties of powders.  Hands on practical session  4 

Determination of interfacial tension between two immiscible liquids and to calculate spreading coefficient.  At the end of the practical student should be able to demonstrate the experiment on interfacial tension  Find out the interfacial tension between two immiscible liquids.  Hands on practical session  4 

Determination of CMC of a surfactant through interfacial tension measurement method.  At the end of the practical student should be able to demonstrate the experiment on CMC of surfactant  Find out the interfacial tension and measurement of CMC.  Hands on practical session  4 

To study the effect of electrolyte on CMC of surfactant  At the end of the practical student should be able to demonstrate the experiment on CMC of surfactant  To find out the effect of electrolyte on CMC of surfactant.  Hands on practical session  4 

Determination of HLB of surfactant.  At the end of the practical student should be able to demonstrate the experiment on HLB of surfactant  To find out the HLB Value.  Hands on practical session  4 

Formulation and evaluation of emulsion  At the end of the practical student should be able to demonstrate the experiment on evaluation of emulsion  To find out the creaking, creaming and phase inversion of emulsion  Hands on practical session  4 

Formulation and evaluation of suspension  At the end of the practical student should be able to demonstrate the experiment on evaluation of suspension  Find out the sedimentation rate and stability study of suspension.  Hands on practical session  4 

Study of effect of particle size on angle of repose and flow properties.  At the end of the practical student should be able to demonstrate the experiment on flow properties  Find out the effect of particle size on flow properties of powers.  Hands on practical session  4 

Determination of relation between dielectric constant of solvent and solubility of drugs.  At the end of the practical student should be able to demonstrate the experiment on solubility  Find out the relation between dielectric constant of solvent and solubility of drugs.  Hands on practical session  4 

To plot ternary phase diagram.  At the end of the practical student should be able to demonstrate the experiment on phase diagram  Draw the ternary phase diagram in the laboratory.  Hands on practical session  4 

Determination of partition coefficient and distribution of drug between two phases.  At the end of the practical student should be able to demonstrate the experiment partition coefficient  Determination of partition coefficient of drug between two immiscible phases.  Hands on practical session  4 

Study of rheograms of some mucilages.  At the end of the practical student should be able to demonstrate the experiment on rheology  Rheograms of some mucilages.  Hands on practical session  4 

Study of effect of fines and lubricant on angle of repose and flow properties.  At the end of the practical student should be able to demonstrate the experiment on flow properties  Find out the effect of different lubricant on flow properties of powders.  Hands on practical session  4 

Determination of bulk density, True density and Granular density of few pharmaceuticals and to calculate porosity of material.  At the end of the practical student should be able to demonstrate the experiment on bulk density  To perform the calculation for the determination of dosage for child.  Hands on practical session  4 

Determination of molecular weight of polymer by viscosity measurement method  At the end of the practical student should be able to demonstrate the experiment on viscosity  Find out the molecular weight of different polymers.  Hands on practical session  4 