Curriculum | PHYSICAL PHARMACEUTICS – I (Practical) | B. Pharmacy

Course: B. Pharmacy 3rd Semester/ 2nd Year

Name of Subject:  PHYSICAL PHARMACEUTICS – I (Practical)

Subject Code:   BP306P

Sr. No.

Contents of the Topic

Learning objectives

Teaching Guidelines

Methodology

Time
(Hrs)

Determination of the solubility of drug at room temperature At the end of the practical student should be able to demonstrate the concept of solubility Find out the solubility of any active pharmaceutical ingredients (API)

Hands on practical session

4

2. Determination of pKa value by Half Neutralization/ Henderson Hassel Balch equation. At the end of the practical student should be able to demonstrate the concept of pKa

To find out the pKa value of the drug sample.

Hands on practical session

4

 3. Determination of Partition co- efficient of benzoic acid in benzene and water At the end of the practical student should be able to demonstrate the concept of partition coefficient

Find out the Partition co- efficient of benzoic acid.

Hands on practical session

4

4.

Determination of Partition co- efficient of Iodine in CCl4 and water

At the end of the practical student should be able to demonstrate the concept of partition coefficient

Find out the Partition co- efficient of iodine.

Hands on practical session

4

5.

Determination of % composition of NaCl in a solution using phenol-water system by CST method

At the end of the practical student should be able to demonstrate the concept of partition coefficient

Determination of % composition of NaCl in a solution

Hands on practical session

46

6.

Determination of particle size, particle size distribution using sieving method

At the end of the practical student should be able to demonstrate the concept of Particle size

Find out the particle size and particle size distribution of given sample in laboratories.

Hands on practical session

4

7.

Determination of particle size, particle size distribution using Microscopic method

At the end of the practical student should be able to demonstrate the concept of particle size

Find out the particle size and particle size distribution of given sample in laboratories.

Hands on practical session

4

 8.

Determination of bulk density, true density and porosity

At the end of the practical student should be able to demonstrate the concept of bulk density

To find out the bulk density, tapped density, angle of repose and other rheological properties of the powders.

Hands on practical session

4

 9.

Determine the angle of repose and influence of lubricant on angle of repose

At the end of the practical student should be able to demonstrate the concept of flow characteristics

To find out the rheological properties of the powders.

Hands on practical session

4

10

Determination of stability constant and donor acceptor ratio of PABA-Caffeine complex by solubility method

At the end of the practical student should be able to demonstrate the concept of solubility

To check the formation of complex by solubility determination method

Hands on practical session

4

11.

Determination of stability constant and donor acceptor ratio of Cupric-Glycine complex by pH titration method

At the end of the practical student should be able to demonstrate the concept of stability

To check the formation of complex by pH titration method

Hands on practical session

4