Curriculum | PHARMACOLOGY-II (Practical) | B. Pharmacy

Course: B. Pharmacy 5th Semester/ 3rd year
Name of Subject: PHARMACOLOGY-II (Practical)
Subject Code:  BP 507 P.

S. No. Contents of the Topics Learning Objectives Teaching Guidelines Methodology Time
(Hrs)
Introduction to in-vitro pharmacology and physiological salt solutions. Student should be able to describe the in-vitro pharmacology and physiological salt solutions
  • Introduction
  • Composition
  • Uses
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Effect of drugs on isolated frog heart. Should be able to describe the Effect of drugs on isolated frog heart.
  • Heart structure
  • Contractions
  • Effect of drugs
  • Procedure
Instructive, Demo in lab, perform the experiment

4

Effect of drugs on blood pressure and heart rate of dog. Student should be able to describe the Effect of drugs on blood pressure and heart rate of dog.
  • Effect of drugs on blood pressure and heart rate of dog
  • Definition of  BP,  Heart Rate
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Study of diuretic activity of drugs using rats/mice. Student should be able to describe the diuretic activity of drugs using rats/mice.
  • Classification of diuretics
  • Drug activity
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

DRC of acetylcholine using frog rectus abdominis muscle. Student should be able to describe the DRC of acetylcholine using frog rectus abdominis muscle
  • DRC of acetylcholine using frog rectus abdominis muscle
  • Procedure
  • Effects
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively. Student should be able to describe the Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively.
  • Synergistic effect of  Physostigmine antagonistic effect atropine by using acetylcholine

Instructive, Demo in lab,  Hands on Practice in laboratory

4

Bioassay of histamine using guinea pig ileum by matching method. Student should be able to describe the Bioassay of histamine using guinea pig ileum by matching method.
  • Identification of histamine
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Bioassay of oxytocin using rat uterine horn by interpolation method. Student should be able to describe the Bioassay of oxytocin using rat uterine horn by interpolation method
  • Identification of oxytocin
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Bioassay of serotonin using rat fundus strip by three point bioassay. Student should be able to describe the Bioassay of serotonin using rat fundus strip by three point bioassay
  • Identification of serotonin
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Bioassay of acetylcholine using rat ileum/colon by four point bioassay. Student should be able to describe the Bioassay of acetylcholine using rat ileum/colon by four point bioassay
  • Identification of acetylcholine
  • Procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Determination of PA2 value of prazosin using rat anococcygeus muscle (by Schilds plot method). Student should be able to describe the PA2 value of prazosin using rat anococcygeus muscle
  • PA2 value definition
  • Procedure
  • Given drug concentration and effect
  • DRC
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Determination of PD2 value using guinea pig ileum. Student should be able to describe the PD2 value using guinea pig ileum
  • PA2 value definition
  • Procedure
  • Given drug concentration and effect
  • DRC
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Effect of spasmogens and spasmolytics using rabbit jejunum. Student should be able to describe the Effect of spasmogens and spasmolytics using rabbit jejunum.
  • Spasmogens and Spasmolytics definition
  • Effect
  • DRC of given sample
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Anti-inflammatory activity of drugs using carrageenan induced paw-edema model In the end of the lab student should be able to describe the Anti-inflammatory activity of drugs using carrageenan induced paw-edema model
  • Anti-inflammatory activity
  • carrageenan induced paw-edema model procedure
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Analgesic activity of drug using central and peripheral methods Student should be able to describe the Analgesic activity of drug using central and peripheral methods
  • Analgesic activity of drug using central and peripheral methods
Instructive, Demo in lab,  Hands on Practice in laboratory

4

Admission 2017