Curriculum | Pharmacognosy and Phytochemistry-II (Theory) | B. Pharmacy

Course: B Pharmacy 3rd Year, 5th Semester

Name of the Subject: Pharmacognosy and Phytochemistry-II (Theory)

Subject Code: BP504T

S. No.

Contents of the Topics

Learning Objectives Teaching Guidelines Methodology Time(Hrs)
1 Metabolic pathways in higher plants and their determination

  • Brief study of basic metabolic pathways and formation of different secondary metabolites through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway.
  • Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
( BY the end of lesson student should be able to)

Describe the various biosynthetic pathways and their investigation

  • Introduction of Primary and secondary metabolites
  • Photosynthesis
  • Shikimic Acid Pathway
  • Acetate Mevalonate Pathway
  • Acetate Malonate Pathway
  • Amino Acid Pathway
  • Radioactive Isotopes
  • Study of utilization of radioactive isotopes in the investigation of Biogenetic studies
—Didactic lecture through power point projection and

—-Use of chemdraw software.

5
2 General introduction, composition, chemistry & chemical classes, general methods of extraction & analysis, biosources, therapeutic uses and commercial applications of following secondary metabolites:
Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,
Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, DigitalisVolatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander.
Iridoids, other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids
describe modern extraction techniques, characterization and identification of phytoconstituents. Alkaloids

  • Definition
  • Types
  • Distribution
  • Chemical Nature
  • Methods of extraction
  • Chemical Tests
  • Therapeutic uses

Glycosides

  • Definition
  • Types
  • Distribution
  • Chemical Nature
  • Methods of extraction
  • Chemical Tests
  • Therapeutic Use

Volatile Oils

  • Definition
  • Types
  • Distribution
  • Chemical Nature
  • Methods of extraction
  • Chemical Tests
  • Therapeutic Use

Biological Source, Morphological Characters, Chemical Constituents and therapeutic uses of following drugs:
Alkaloids:
Vinca
Rauwolfia, Belladonna
Opium,
Phenylpropanoids and Flavonoids: Lignans
Tea
Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice
Dioscorea
Digitalis

Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander.
Iridoids, other terpenoids & Naphthaquinones:
Gentian, Artemisia, taxus, carotenoids

Instructive and video tutorials. 20
3 Industrial production, estimation and utilization of the following phytoconstituents:
Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine,
Taxol, Vincristine and Vinblastine
Describe the production and utilization of phytoconstituents at industrial scale. Industrial production, estimation and utilization of the following phytoconstituents:

  • Forskolin,
  • Sennoside,
  • Artemisinin,
  • Diosgenin,
  • Digoxin,
  • Atropine,
  • Podophyllotoxin,
  • Caffeine,
  • Taxol,
  • Vincristine
  • Vinblastine
—Instructive —-video Lectures
—Tutorials.
10
4 Basics of Phytochemistry

Modern methods of extraction, application of latest techniques like Spectroscopy, chromatography and electrophoresis in the isolation, purification and identification of crude drugs.

Explain the techniques extraction, isolation, characterization and identification of phytoconstituents Extraction

  • Different types of Extraction Methods

Chromatography

  • Types
  • Adsorption Chromatography
  • Partition Chromatography
  • Use of Chromatography in Isolation, purification and identification of crude drugs

Spectroscopy
Brief introduction about

  • UV, IR, NMR, Mass Use of Spectroscopy in Isolation, purification and identification of crude drugs

Electrophoresis

  • Brief introduction
  • Use of Electrophoresis in Isolation, purification and identification of crude drugs
Instructive, Power point presentation and video tutorials. 10