Curriculum | PHARMACEUTICAL INORGANIC CHEMISTRY (Theory) | B. Pharmacy

B. Pharmacy Semester- Ist / 1st year
PHARMACEUTICAL INORGANIC CHEMISTRY (Theory)
BP104T
S. No Contents of the Topics Learning Objectives Teaching Guidelines Methodology Assessment Tools Time Allocated
Impurities in pharmaceutical substances: History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate

 

General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes

 

 

(At the end of the lecture the student should be able to)

explain  what is impurity/source of impurity/ limit test/application /procedure/principle involved in limit tests

 

 

Explain preparation method and medicinal uses for various inorganic compounds/assay procedure/identification test/percent purity etc.

 

History, sources and types of impurities, principle involved in the limit tests Instructive

 

 

 

Marker and Board

 

 

 

 

 

Power point presentations

 

Objective type

 

 

 

 

Class test

 

 

Multiple Choice Question

 

6

 

 

 

 

 

 

 

 

4

 

Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.

 

 

 

Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance.

 

Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.

 

 

Know the concept of acid and base. enumerate buffers and their preparation and stability procedure.

discuss isotonicity and their calculation methods/application/ measurement methods etc.

 

 

Discuss about electrolytes ,types of electrolytes and their application in pharmaceutical industry/replacement therapy/combination therapy/Ringer solution/ Physiological  acid base balance

 

 

 

Explain Dental products  like DENTIFRICES,DENTAL CARIES/DESENSITIZING AGENTS/POLISHING AGENTS ETC.

Buffers in pharmaceutical systems, measurement and calculation of isotonicity

 

Functions of major physiological ions

 

 

 

 

 

Dental products

Instructive

 

 

 

Marker and Board

 

 

Power point presentations

 

 

Represent various market products related to electrolytes

 

 

 

 

 

 

Demonstration of various market products related to dental caries (pepsodent)

Objective type class test,

 

Multiple hoice Question

 

Oral Discussion

 

 

presentation

 

 

 

 

 

 

 

 

 

Oral Discussion

 

4

 

 

 

 

 

 

 

 

 

 

4

 

 

 

 

 

 

 

 

 

 

2

Gastrointestinal agents

 

Acidifiers: Ammonium chloride* and Dil. HCl

 

Antacid:   Ideal properties of antacids, combinations of antacids, Sodium

Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture

 

Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite

 

Antimicrobials: Mechanism, classification, Potassium permanganate, Boric acid, Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations

 

 

Explain acidifiers, cathartics and antacids  with their properties, applications.

 

Discuss about antimicrobial compounds  in details

 

 

 

 

 

 

 

 

Acidifiers, antacids, cathartics, antimicrobials

 

 

Demonstration of various market products related to antacid, cathartics and antimicrobial

 

Marker and Board

 

 

 

Power point presentations

 

 

 

Objective type

 

 

 

class test

 

10
Miscellaneous compounds

Expectorants-potassium iodide and ammonium chloride

Emetics-copper sulphate ,sodium potassium tartarate

Heamatinics-ferrous sulphate and ferrous gluconate

 

Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite333

 

Astringents: Zinc Sulphate, Potash Alum

 

Know what are expectorants ,emetics and Heamatinics with their compounds and their properties /uses/ application

 

explain the concept  of astringents and antidote and their properties /application /uses

compounds,

Expectorants

Emetics

Poison and Antidote

Astringents

 

Marker and Board

 

 

Problem based learning

 

 

 

Power point presentations

 

Objective type

 

 

 

 

Class test

 

 

Multiple Choice Question

 

8
Radiopharmaceuticals:  Radio  activity,  Measurement  of  radioactivity,

Properties of α, β, γ radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide I131, Storage conditions, precautions & pharmaceutical application of radioactive substances.

 

Know What are isotopes/properties  of  alpha ,beta, gamma rays/Account of radioactivity/stability of compounds/measurements of radioactivity  (GM Counter) and storage conditions ,preparations and pharmaceutical applications of radioactive substances Properties of Radiopharmaceuticals  

 

Power point presentations

 

Marker and BoardPower point presentations

 

Objective type

 

Class assignments

 

Multiple Choice Question

 

7
Admission 2017