Curriculum | Pharmaceutical Analysis I Theory | B. Pharmacy

Course : B. Pharmacy    Semester -1 st  / Year 1st
Pharmaceutical Analysis -I–Theory
BP102T
S. No Contents of the Topics Learning Objectives Teaching Guidelines Methodology Assessment Tools Time Allocated
1 Pharmaceutical analysis– Definition and scope

 

Different techniques of analysis Methods of expressing concentration Primary and secondary standards. Preparation and standardization of various molar and normal solutions-Oxalic acid, sodium hydroxide, hydrochloric acid, sodium thiosulphate, sulphuric acid, potassium permanganate and ceric ammonium sulphate

Errors: Sources of errors, types of errors, methods of minimizing errors, accuracy, precision and significant figures

(At the end of the lecture the student should be able to: )

describe what are  analytical techniques/methods for determining concentration//primary and secondary standards/their preparation and standardization procedure/

Define  the terms normality/molarities/molality for example how to prepare  1M NaOH Solution

clarify the errors, accuracy, precision

Different techniques of analysis Methods of expressing concentration Primary and secondary standards. Preparation and standardization of various molar and normal solutions-Oxalic acid, sodium hydroxide, hydrochloric acid, sodium thiosulphate, sulphuric acid, potassium permanganate and ceric ammonium sulphate

Errors: Sources of errors, types of errors, methods of minimizing errors, accuracy, precision and significant figures

Problem based Learning

 

 

 

 

Power point presentations

 

Objective type

 

 

 

 

Class test

 

 

Multiple Choice Question

 

5

 

 

 

 

 

 

 

 

 

 

 

 

5

2  

Acid base titration: Theories of acid base indicators, classification of acid base titrations and theory involved in titrations of strong, weak, and very weak acids and bases, neutralization curves

 

-Non aqueous titration: Solvents, acidimetry and alkalimetry titration and estimation of Sodium benzoate and Ephedrine HCl

 

explain the concept of acid and base ,theories, indicators, strong acid and base/ neutralization curves

 

 

 

 

explain Non aqueous titration, solvents/acidimetry, alkalimetry & their compounds  properties/application/identification test/assay methods

Theories of acid base indicators, classification of acid base titrations and theory involved in titrations of strong,

 

Small group Discussion

 

Power point presentations

Problem Based Learning

Student seminar

Teacher Seminar

 

Objective type class test,

 

Multiple Choice Question

 

Oral Discussion

 

 

Take presentation

 

 

 

5

 

 

 

 

 

 

 

 

 

 

 

 

5

3 Precipitation   titrations: Mohr’s   method,   Volhard’s,   Modified Volhard’s, Fajans method,   estimation of sodium chloride.

 

 

 

Complexometric titration: Classification, metal ion indicators, masking and demasking reagents, estimation of Magnesium sulphate, and calcium gluconate.

 

 

 

Gravimetry: Principle and steps involved in gravimetric analysis. Purity of the precipitate: co-precipitation and post precipitation, Estimation of barium sulphate

.

 

 

Clarify Precipitation   titrations, Mohr’s   method,   Volhard’s,   Modified Volhard’s, Fajans method & estimation procedure for  NaCl

 

 

 

Explain complexometric titration,classification,indicators,masking & demasking reagents

 

 

 

Clarify gravimetry,principle,steps, Purity of the precipitate: co-precipitation and post precipitation & estimation procedure for BaCl

Mohr’s   method,   Volhard’s,   Modified Volhard’s, Fajans method,   estimation of sodium chloride.

Classification, metal ion indicators, masking and demasking reagents, estimation of Magnesium sulphate, and calcium gluconate

Principle and steps involved in gravimetric analysis. Purity of the precipitate: co-precipitation and post precipitation, Estimation of barium sulphate

 

Students seminar  

 

Objective type

 

 

 

class test

 

 

assignments

4

 

 

 

 

 

 

 

3

 

 

 

 

 

 

 

3

4 –          Redox titrations

 

Concepts of oxidation and reduction

 

Types of redox titrations (Principles and applications)

 

 

–          Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry, Titration with potassium iodate

Define  redox titration, its ,types, principle  & application

 

 

 

 

Explain Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry titration with their compounds

Concepts of oxidation and reduction

 

Types of redox titrations (Principles and applications

Cooperative Learning

 

Problem Based Learning

Student seminar

Teacher Seminar

 

 

 

 

 

 

Power point presentations

 

Objective type

 

 

 

class test

 

 

assignments

4

 

 

 

 

 

4

5  

Electrochemical methods of analysis

 

Conductometry– Introduction, Conductivity cell, Conductometric titrations, applications

 

Potentiometry – Electrochemical cell, construction and working of reference (Standard hydrogen, silver chloride electrode and calomel electrode) and indicator electrodes (metal electrodes and glass electrode), methods to determine end point of potentiometric titration and applications.

 

Polarography – Principle, Ilkovic equation, construction and working of dropping mercury electrode and rotating platinum electrode, applications

.

 

basic principal of conductometery, titration and its applications

 

 

 

 

 

 

Clarify the potentiometer (potential ),electrode,srandard,reference,indicators ,methodology for determine end point  & its applications

 

 

 

 

 

 

Clarify the  polarography, principle, llkovic equation ,construction, working of dropping mercury electrode ,rotating platinum electrode & its  application

 

Introduction,

Conductivity cell

Conductometric titrations

 

Applications

 

Electrochemical cell, construction and working of reference and indicator electrodes, methods to determine end point of potentiometric titration and applications.

Principle, Ilkovic equation, construction, working and applications dropping mercury electrode and rotating platinum electrode

 

 

Simulation

 

Power point presentations

 

 

 

Objective type

 

 

 

class test

 

 

assignments

 

 

2

 

 

 

 

 

 

3

 

 

 

 

 

 

 

 

 

2

Admission 2017