Curriculum | Novel drug Delivery system (Theory) | B. Pharmacy

Course: B. Pharmacy VIIth  Semester/ 4th   Year
Name of Subject: Novel drug Delivery system  (Theory)
Subject Code:  BP 704 T

 

Sr. No. Contents if the Topic Learning objectives Teaching Guidelines Methodology Time

(Hrs)

1.       Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates. Approaches to design controlled release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release formulations

 

Polymers: Introduction, classification, properties, advantages and application of polymers in formulation of controlled release drug delivery systems.

Upon completion of the course student shall be able

1. To understand various approaches for development of novel drug delivery systems.

2. To understand the criteria for selection of drugs and polymers for the development of

Novel drug delivery systems, their formulation and evaluation

      Introduction, Definition, advantages,disadvantages

Approaches,dissolution and ionexchange principles, Physicochemical and biological properties of drugs relevant to controlled release formulations

Study of polymers special reference to its classification,properties,advantages and its application

 

 

 

Didactic

PowerPoint Demonstration

Industry Visit

Lab Practicals

10
2.       Microencapsulation: Definition, advantages and disadvantages, microspheres

/microcapsules, microparticles, methods of microencapsulation, applications

Mucosal Drug Delivery system: Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems

Implantable Drug Delivery Systems:Introduction, advantages and disadvantages, concept of implantsand osmotic pump

Upon completion of the course student shall be able

1. To understand various approaches for development of novel drug delivery systems.

2. To understand the criteria for selection of drugs and polymers for the development of

Novel drug delivery systems, their formulation and evaluation like microencapsulations, mucosal and implantable drug delivery systems

Detail study of microencapsulation including: Definition, advantages and disadvantages, microspheres

/microcapsules, microparticles, methods of microencapsulation, applications .

Explain mucosal Drug delivery system its introduction,  Introduction, Principles of bioadhesion / mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and formulation considerations of buccal delivery systems

Implantable Drug Delivery Systems:Introduction, advantages and disadvantages, concept of implantsand osmotic pump

 

Didactic

PowerPoint Demonstration

Industry Visit

Lab Practicals

10
3.       Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive systems and their applications

Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers

Upon completion of the course student shall be able

1. To understand various approaches for development of novel drug delivery systems.

2. To understand the criteria for selection of drugs and polymers for the development of

Novel drug delivery systems, their formulation and evaluation like Transdermal and naso pulmonary systems

Introduction of Transdermal Drug Delivery Systems,permeation,factors, Componentsof TDDS and its formulation approaches.

Study of Gastroretentive drug delivery systems: Introduction, advantages, disadvantages, approaches for GRDDS – Floating, high density systems, inflatable and gastroadhesive systems and their applications

Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays, nebulizers

Didactic

PowerPoint Demonstration

Industry Visit

Lab Practicals

10
4.       Targeted drug Delivery: Concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications Upon completion of the course student shall be able

1. To understand various approaches for development of novel drug delivery systems.

2. To understand the criteria for selection of drugs and polymers for the development of

Novel drug delivery systems, their formulation and evaluation like targeted drug delivery concepts

 

Explain Targeted drug delivery concepts and approaches advantages and disadvantages, introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their applications

Didactic

PowerPoint Demonstration

Industry Visit

Lab Practicals

08
5.       Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to overcome –Preliminary study, ocular formulations and ocuserts

Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages, development of intra uterine devices (IUDs) and applications

Upon completion of the course student shall be able

1. To understand various approaches for development of novel drug delivery systems.

2. To understand the criteria for selection of drugs and polymers for the development of

Novel drug delivery systems, their formulation and evaluation like Ocular and intrauterine Drug Delivery Systems

introduction of Ocular Drug Delivery Systems,intra ocular barriers and methods , , ocular formulations and ocuserts

Intrauterine Drug Delivery Systems intra uterine devices (IUDs) and applications

Didactic

PowerPoint Demonstration

Industry Visit

Lab Practicals

07
Admission 2017